J Korean Acad Pediatr Dent. 2012;39(4): 366-372.
Soo-Yung Kim1, Nam-Ki Choi1, Ji-Il Park2, Seon-Mi Kim1
1Department of Pediatric Dentistry, School of Dentistry, Chonnam National University
2Department of Dental Hygiene, Gwangju Health College
Corresponding Author: Seon-Mi Kim ,Tel: 062-530-5668, Email: smkim1406@hanmail.net
Received: May 13, 2012;  Accepted: October 13, 2012.
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The aim of this study was to compare two commercial root canal medicaments, ProRoot MTA (Dentsply Tulsa, USA) and OrthoMTA (Bio MTA, Korea), by assessing the antimicrobial effects on three selected species commonly found in root canals of infected teeth, namely Enterococcus faecalis, Fusobacterium nucleatum and Staphylococcus epidermidis. Colonies of these bacteria were treated with varied concentrations of ProRoot MTA or OrthoMTA over different lengths of time. The results are as follows : 50, 25 and 12.5 mg/mL of ProRoot MTA or OrthoMTA did not completely inhibit the growth of E. faecalis, but a decreased growth rate was evident in comparison to the control (p < 0.05). 50 mg/mL of both materials successfully eliminated F. nucleatum during the first 24 hours. Regrowth of microbes after 24 hours, however, indicated a diminished effect of ProRoot MTA whereas OrthoMTA showed its continuously sustained antimicrobial actions (p < 0.05). 50 mg/mL of ProRoot MTA and 50, 25 mg/mL of OrthoMTA exerted their full antibacterial actions against S. epidermidis during the first 24 hours. Although the regrowth of colony was observed after 24 hours, the rate of growth was significantly decreased, approximating a complete inhibition (p < 0.05). The present study revealed that OrthoMTA, recently developed in Korea, had antimicrobial activity higher than ProRoot MTA.
Keywords: Antimicrobial effects | OrthoMTA | ProRoot MTA
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