J Korean Acad Pediatr Dent. 2007;34(1): 130-139.
THE DENTAL CARIES, CARIOGENIC MICROORGANISMS AND LEVELS OF SALIVARY IMMUNOGLOBULIN IN SUBJECTS WITH DOWN'S SYNDROME
김선미1, 양규호1, 최남기1, 강미선2, 임회순3, 오종석4
1전남대학교 치의학전문대학원 소아치과학교실 및 치의학 연구소
2전남대학교 치의학전문대학원 2단계 BK21
3전남대학교 치의학전문대학원 치과교육학교실
4전남대학교 의과대학 미생물학교실
Corresponding Author: 김선미 ,
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ABSTRACT
This study investigated the relationship between dental caries and various oral factors in subjects with Down's syndrome. We compared 25 subjects with Down's syndrome with 63 healthy control. The dental caries index and plaque index were examined, and the total salivary immunoglobulin A and S. mutans specific salivary immunoglobulin A concentration were measured using ELISA. The S. mutans counts, Lactobacillus counts and buffer capacity were measured with Dentocult test medium. The decayed and filled surface index of deciduous teeth in subjects with Down's syndrome was lower than in controls(p<0.001). The plaque index and total salivary immunoglobulin A concentration showed no difference, S. mutans specific salivary immunoglobulin A concentration and buffer capacity in subjects with Down's syndrome were lower than in controls(p<0.001). There was no significant difference between two groups in the S. mutans counts and Lactobacillus counts. In 9-11 year age group, S. mutans counts in subjects with Down's syndrome was lower than in controls(p<0.001) and S. mutans specific salivary immunoglobulin A concentration was lower(p<0.05). There was a high correlation among deciduous dental caries index and buffering capacity and S. mutans counts.
Keywords: Down's syndrome | Dental caries | Streptococcus mutans | Buffer capacity | Salivary immunoglobulin A | Streptococcus mutans-specific salivary immunoglobulin A
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