Journal of the Korean Academy of Pediatric Dentistry 2008;35(1):57-64.
Published online February 29, 2008.
THE ANALYSIS OF REMINERALIZATION EFFECT IN FLUORIDE VARNISH USING CONFOCAL LASER SCANNING MICROSCOPE
Ji-Hoon Kwon, Ho-Won Park, Ju-Hyun Lee, Hyun-Woo Seo
Department of Pediatric Dentistry, Oral Science Research Center, College of Dentistry, Kangnung National University 
공초점 레이저 주사 현미경을 이용한 불소 바니쉬 재광화 효과의 분석
권지훈, 박호원, 이주현, 서현우
강릉대학교 치과대학 소아치과학교실 및 구강과학연구소
Correspondence:  Ju-Hyun Lee,  Tel: 033-640-3158, Email: ljh55@kangnung.ac.kr
Abstract
It is well established that fluoride products play an important role in the prevention and remineralization of carious lesion. Fluoride varnish is a concentrated topical fluoride and varnishes adhere to tooth surface, permitting prolonged fluoride exposure and uptake. In this study, the artificial initial enamel caries was caused on the sound human enamel and divided 60 specimens into three groups. Group 1 and group 2 were treated with the topical application of fluoride varnish and stored in artificial saliva for 1 and 2 weeks. Group 3 was stored in artificial saliva for 2 weeks, which acted as control group. Changes in mineral contents were analysed with the confocal laser scanning microscope. The following results were obtained: 1. In group 1 and group 2, the total fluorescence of the lesion(TFL) was reduced in remineralized area compared to in demineralized area(p<0.05). 2. The total fluorescence of the lesion of remineralized area was more reduced in group 2 than in group 1(p<0.05). 3. The total fluorescence of the lesion was more reduced in group 2 than in control group(p<0.05). 4. Confocal laser scanning microscope can be used in quantitative analysis of remineralization by fluoride varnish.
Key Words: Fluoride varnish, Remineralization, Confocal laser scanning microscope


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