J Korean Acad Pediatr Dent. 2007;34(4): 632-638.
THE ANTICARIOGENIC EFFECTS OF XYLITOL ON MUTANS STREPTOCOCCI IN CHILDREN WITH MIXED DENTITION
Jae-Hong Park
Department of Pediatric Dentistry and Institute of Oral Biology, School of Dentistry, Kyung Hee University
Corresponding Author: Jae-Hong Park ,Tel: 82-2-958-9379, Fax: 82-2-965-7247, Email: pedopjh@khu.ac.kr
Share :  
ABSTRACT
The purpose of this study was to investigate the effect of xylitol chewing gums on mutans streptococci (MS) counts in saliva. Sixty two children 6 to 11 years old were randomly assigned into one of three groups. Stimulated saliva specimens were plated in duplicate on conventional selective culture (mitis salivarius kanamycin bacitracin agar) for mutans streptococci. Polymerase chain reaction (PCR) amplication was performed to identify MS. After the 4-month period a significant decrease of the MS counts occurred in the group B (two gum 3 times a day; P < 0.05) but not in group A (one gum 3 times a day) and control group (didn't receive xylitol gum). According to qualitative evaluations, xylitol use did reduce the levels of MS in mixed dentition children. It has been suggested that a daily intake of 2 tablet for 3 times a day (about 10g) is needed in order to obtain a clinical anticariogenic effect.
Keywords: Xylitol | mutans streptococci | Stimulated saliva | Dental caries
Editorial Office
Seoul National University, Dental Hospital, B1-166 101, Daehak-ro, Jongno-gu, Seoul, 110-744
Tel. +82-70-4145-8875,    Fax. +82-2-745-8875   E-mail : kapd59@kapd.org

Copyright© Korean Academy of Pediatric Dentistry. All right reserved.                powerd by m2community
About |  Browse Articles |  Current Issue |  For Authors and Reviewers