Journal of the Korean Academy of Pediatric Dentistry 2011;38(2):155-160.
Published online May 31, 2011.
The influence of Lactobacillus rhamnosus GG on the binding ability of Streptococcus mutans
Su-Jun Lee1, Sung-Hoon Lee2, Bong-Kyu Choi2, Jung-Wook Kim1, Young-Jae Kim1, Chong-Chul Kim1
1서울대학교 치의학대학원 소아치과학교실, 치학연구소
2서울대학교 치의학대학원 구강미생물학교실, 치학연구소 
Lactobacillus rhamnosus GG가 Streptococcus mutans의 부착능에 미치는 영향
이수전1, 이성훈2, 최봉규2, 김정욱1, 김영재1, 김종철1
1서울대학교 치의학대학원 소아치과학교실, 치학연구소
2서울대학교 치의학대학원 구강미생물학교실, 치학연구소
Correspondence:  Chong-Chul Kim, 
Received: 30 November 2011   • Accepted: 8 March 2011
Abstract
Probiotics has currently attracted for means of preventive treatment measurement instead of using non-specific and broad spectrum antimicrobials. In previous studies, two main probiotics species, Lactobacillus and Bifidobateria, showed the reduction of DMFS and S. mutans counts. However, the timing of introducing probiotic species to oral cavity is not clear. The aim of this study is to evaluate the changes of binding ability of S. mutans in various concentrations and inoculation time of L. rhamnosus GG. Adding the following concentration of L. rhamnosus GG, 1×106 CFU, 1×107 CFU and 1×108 CFU, to S. mutans medium demonstrates significant reduction of S. mutans counts. Additionally, more reduction was observed when L. rhamnosus were inoculated prior to S. mutans or simultaneously inoculated compared to when S. mutans were inoculated prior to L. rhamnosus after 3 hours of incubation. Based on this research, the timing of introducing probiotics should be considered when probiotics are utilized as a preventive treatment measurement.
Key Words: Probiotics, Lactobacillus rhamnosus, Streptococcus mutans
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