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J Korean Acad Pediatr Dent. 1999;26(2): 331-338.
EFFECT OF CHEMORADIATION THERAPY ON THE DEVELOPING DENTITION : A CASE REPORT
김재곤, 김영신, 양정숙, 이승영, 백병주
전북대학교 치과대학 소아치과학교실 및 구강생체과학연구소
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ABSTRACT
Chemoradiation therapy used on pediatric oncology patients often causes dental developmental anomalies that affect future dental care. Defects noted include tooth and root agenesis, root thining and shortening, and localized enamel defects. The effect of radiotherapy usually are confined to the radiation site, but the effects of chemotherapy may be more wide spread because of its systemic distribution and structures and organs unrelated to the primary tumor may be affected. Many pediatric cancers are treated with a combination of radiation and multiagent chemotherapy to create synergic and additive effects. Dental treatment affected by chemoradiation damage to developing teeth includes orthodontic tooth movement, prosthetic abutment considerations, periodontal health, space maintenance, requirements for home fluoride regimens to protect hypomineralized areas, restoration options for hypoplastic/hypomineralized teeth, and endodontic procedures. The following case demonstrate chemoradiation therapy effects on the dental development.
Keywords: chemoradiation therapy | developing dentition | root agenesis
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