| A CLINICAL AND BACTERIOLOGICAL EXAMINATION AND TREATMENT OF PAPILLON-LEFEVRE SYNDROME |
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| Papillon-Lefevre Syndrome의 임상 및 미생물학적 검사와 치료 |
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백병주1, 김재곤1, 김문현1, 김형섭2, 송요한3 |
1전북대학교 치과대학 소아치과학교실 및 치의학연구소
2전북대학교 치과대학 치주과학교실 및 치의학연구소
3전북대학교 치과대학 구강미생물학교실 및 치의학연구소 |
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| Abstract |
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The Papillon-Lefevre Syndrome(PLS), a disease with autosomal recessive inheritance, is characterized by diffuse hyperkeratosis of the palms and soles, mostly prepubertal periodontitis and premature loss of primary and permanent dentition. The etiology of the destruction of periodontal tissues has not been completely clarified. In recent years, two main factors are suggested to be responsible for tooth loss ; firstly, the presence of gram negative microorganisms in the periodontal pockets of the patients. The other factor suggested is cellular deficiency in chemotaxic and phagocytic function of neutrophylic granulocytes. Resent data suggestes that mechanical debridement in conjunction with antibiotic therapy may be successful in periodontal management of Papillon-Lefevre Syndrome, particularly if administered early. In this study, a Papillon-Lefevre Syndrome patient was studied clinically, radiologically, histopathologically and microbiologically. 5 years female patient with gingival swelling and destruction of periodontal structure on the whole dentition were examined and palmar and plantar hyperkeratosis were can be seen. On microbiological analysis, Actinobacillus actino-mycetemcomitans was performed. Concurrently, the children recieved extraction of maxillary anterior teeth and construction of removable prosthetis. The combination of professional oral hygiene care and antibiotic therapy improved the dermatologic and periodontal condition. |
| Key Words:
Hyperkeratosis, Papillon-Lefevre Syndrome, prepubertal periodontitis, autosomal recessive inheritance |
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