CLINICAL STUDY ON THE CONSCIOUS SEDATION WITH MIDAZOLAM INTRANASAL SPRAY

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Journal of the Korean Academy of Pediatric Dentistry 1998;25(4):782-787.
Published online November 30, 1998.

CLINICAL STUDY ON THE CONSCIOUS SEDATION WITH MIDAZOLAM INTRANASAL SPRAY

미다졸람의 비강내 분무를 이용한 의식진정에 대한 증례보고

김현식, 최정림, 이창섭, 이상호

조선대학교 치과대학 구강생물학 연구소

Abstract

The treatment for pediatric dental patient has become more complex than the previous, because patients of pediatric dentistry, younger than the previous, and they were often combined with systemic disease. And, the importnace of conscious sedation has been increased by this time for this reason. In a variety of CNS depressants, newly developed imidazobenzodiazepine (midazolam) is well known as a safe and effective medicament. It has a rapid onset, minimized cardiovascular depression and various possible administering, route, so it is commonly used for the conscious sedation of pediatric dental patients. Recently, "intranasal drop-in method" draws attention for its safety, but discomfort during administration and posterior dripping through pharynx diminish its popularity. Now more advanced method for intranasal administration is introduced for conscious sedation for pediatric dental patients, it is "intranasal spray" with aerosol form of medicament. With this method, we can achieve some benefits as belows : 1. Diminished discomfort during intranasal spray than nitranasal drop-in. 2. Rapid osnet and reduction than intranasal drop-in. 3. Eliminatin of adverse reaction, such as rhinorrhea. 4. More improved behavior rating scale.

Key Words: conscious sedation, intranasal spray, midazolam