| A STUDY ON THE CELL PROPERTY OF XYLITOL-RESISTANT STREPTOCOCCUS MUTANS AND XYLITOL-SENSITIVE STREPTOCOCCUS MUTANS |
| |
| Xylitol-resistant Streptococcus mutans와 xylitol-sensitive Streptococcus mutans의 세포 성질에 관한 비교연구 |
|
이홍모, 김정욱, 장기택, 이상훈, 한세현, 김종철 |
|
서울대학교 치과대학 소아치과학교실 |
Correspondence:
,
|
|
|
|
|
| Abstract |
|
Xylitol has been used as sugar substitute to prevent dental caries. It is not fermented by most dental plaque bacteria and interferes with the growth of mutans streptococci. Therefore the production of acidic metabolites and the growth of mutans streptococci are inhibited. S. mutans strains which are inhibited to grow under the presence of xylitol are referred as xylitol-sensitive (XS) strains. However, experimental and clinical studies have shown that there were mutated groups of S. mutans strains that are not affected by xylitol. They are referred as xylitol-resistant(XR) strains. The aim of the present study was to investigate that emergence of XR strain would effect on the anticariogenecity of xylitol by comparing the growth rate, the extracellular pH, hydroxyapatite adhesion and the agglutination of the XR/XS strains. Overall we came out with following results : 1. No difference in the growth rate and the extracellular pH was found between the XS strain and the XR strain. 2. No difference in adhesion to hydroxyapatite surface was found between the XR strain and the XS strain (p>0.05) and adhesion of the XS strain was greater than that of XR strain in the sucrose-dependent adhesion to hydroxyapatite (p<0.05). 3. The XR strain was agglutinated in the lower concentration of saliva than that of XS strains. |
| Key Words:
Xylitol, Streptococcus mutans, Xylitol-resistant, Hydroxyapatite adhesion, Agglutination |
|
PDF Links
Download Citation
