Journal of the Korean Academy of Pediatric Dentistry 2009;36(1):38-45.
Published online February 28, 2009.
COMPARATIVE STUDY OF THE REMINERALIZATION EFFECTS USING CPP-ACP AND FLUORIDE ON THE ARTIFICIAL ENAMEL LESION
Ki-baek Kim, Nam-ki Choi, Seon-mi Kim, Kyu-ho Yang
Department of Pediatric Dentistry, Chonnam National University School of Dentistry, Dental Research Institute and Second stage of BK21 
CPP-ACP 함유 크림과 불소가 초기 인공우식 법랑질에 미치는 재광화 효과에 대한 비교 연구
김기백, 최남기, 김선미, 양규호
전남대학교 치의학전문대학원 소아치과학교실 및 치의학연구소 및 2단계 BK21
Correspondence:  Kyu-ho Yang,  Tel: /062-530-5668, Email: hellopedo@hanmail.net
Received: 26 May 2008   • Accepted: 1 December 2008
Abstract
he aim of this study was to examine efficacy of the commercially available 10% CPP-ACP cream (Tooth mousse, GC Co., Japan) and/or 0.05% NaF solution on the remineralization of artifical caries-like lesion in the bovine teeth enamel. Sixty bovine teeth were embedded in orthodontic resin and flattened. The enamel surface in 3 mm diameter was exposed with nail varnish. Specimens were stored in demineralizing solution and divided 5 groups; Group 1 (No treatment), 2 (0.05% NaF solution 1 min), 3 (Tooth mousse 3 min), 4 (After 0.05% NaF solution, Tooth mousse treatment), and 5 (After Tooth mousse treatment, soaking in 0.05% NaF solution during 1 min). After treatment by groups, all specimens was stored in artificial saliva for 30 min. After the process described as above was performed during 10 days without pH cycling, surface hardness (Vickers Hardness Number, VHN) was tested and analyzed by paired t-test and one-way ANOVA test with SPSS 14.0. In intragroup comparison between surface hardness of pre and post-treatment, group 3, 4, 5 showed statistically significant increase (P < 0.05). In intergroup comparison among surface hardness increase of all groups, difference of group 5 between pre and post-treatment (15.80±12.2) was the highest, and followed by group 4 (14.27±11.73), 3 (4.05±5.18), 2 (1.15±6.83), 1 (0.78±6.21). Tooth mousse can be a good alternative agent for the fluoride, and the combination use with fluoride might have the additional anticariogenic effect.
Key Words: CPP-ACP, Tooth mousse, Sodium fluoride, Remineralization


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