| A HISTOLOGICAL CHANGES AND CGRP EXPRESSION AFTER EXPOSURE INJURY BY ER:YAG LASER IN DENTAL PULP OF RAT |
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Jae-Ho Yang2, Jong-Tae Park2, Kyu-Tag Kim2, Sang-Bong Kim2, Nan-Young Lee1, Sang-Ho Lee1, Heung-Joong Kim2 |
1Department of Pediatric Dentistry,College of Dentistry, Chosun University
2Oral Biology Research Institute & Post BK21,College of Dentistry, Chosun University |
| 흰쥐 치수에서 Er:YAG laser에 의한 노출손상에 따른 조직학적 변화 및 CGRP 단백질의 발현 |
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양재호2, 박종태2, 김규탁2, 김상봉2, 이난영1, 이상호1, 김흥중2 |
1조선대학교 치과대학 소아치과학교실
2구강생물학연구소 및 2단계 BK21 |
Correspondence:
Heung-Joong Kim, Tel: 062-230-6875, Email: hjbkim@chosun.ac.kr
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| Abstract |
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The purpose of this study was to investigate early histological changes and calcitonin gene-related peptide (CGRP) expression in the dental pulp of the rat after Er:YAG laser preparation. Occlusal cavities were prepared in the upper first molars using either Er:YAG laser and conventional bur. At 48 hours after cavity preparation, the teeth were processed for hematoxylin-eosin stain and CGRP immunohistochemistry. The results were as follows : 1. The cavity floor by Er:YAG laser preparation was more irregular shape compared with those by bur preparation and there are some cracks in the directions of dentinal tubules. 2. There were more inflammatory cell infiltration and disruption of odontoblast in the dental pulp by Er:YAG laser preparation in comparison with the dental pulp by bur preparation. 3. CGRP expression in the pulp tissue by both Er:YAG laser and bur preparations were increased and higher than in the normal pulp. The expression pattern of CGRP was more strong in the pulp by Er:YAG laser preparation. These results indicate that Er:YAG laser is useful in the operative dentistry such as caries removal and cavity preparation if properly applied. |
| Key Words:
Calcitonin gene-related peptide, Dental pulp, Er:YAG laser, Immunohistochemistry |
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