Journal of the Korean Academy of Pediatric Dentistry 2012;39(2):174-180.
Published online May 31, 2012.
REGENERATIVE ENDODONTIC TREATMENT OF IMMATURE PERMANENT TEETH BY USING PLATELET-RICH FIBRIN
Hana Kim, Nan-Young Lee, Sang-Ho Lee
Department of Pediatric Dentistry, College of Dentistry, Chosun University 
치근단 병변이 있는 미성숙 영구치에서 Platelet-rich fibrin(PRF)를 이용한 보존적 근관치료
김하나, 이난영, 이상호
조선대학교 치과병원 소아치과학교실
Correspondence:  Nan-Young Lee,  Tel: 062-220-3867, Email: nandent@chosun.ac.kr
Received: 6 February 2012   • Accepted: 10 May 2012
Abstract
n case of an immature tooth with necrotic pulp, regeneration of pulp tissue into a canal would be the ideal outcome. It may be capable of promoting the continuation of normal root development. Platelet-rich fibrin has been suggested as a potentially ideal scaffold for regenerative endodontic treatment. Immature permanent teeth of young children were diagnosed with pulp necrosis and apical abscess as the result of clinical and radiographic examination. After removal of necrotic pulp, canal was irrigated with 5.25% NaOCl and dried with paper point. A triple antibiotic mixture was placed in canal space in 3 weeks. After removal of the antibiotic mixture, the platelet-rich fibrin was injected into the canal space with MTA placed directly over the platelet-rich fibrin clot. The coronal region was restored by composite resin. On the basis of short-term results of the present 3 cases, regeneration of vital tissues appears to be possible in a tooth with necrotic pulp and a periapical lesion. Also, platelet-rich fibrin proves to be potentially an ideal scaffold for this procedure. Therefore, long-term clinical observation and examination about this treatment using platelet-rich fibrin in immature permanent teeth of young children are considered to be necessary.
Key Words: Regenerative endodontic treatment, Triple antibiotic mixture, Platelet-rich fibrin


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