Journal of the Korean Academy of Pediatric Dentistry 2012;39(1):26-33.
Published online February 29, 2012.
A CONTROL OF PLAQUE, GINGIVITIS AND ANTI-CARIES EFFECT OF DENTIFRICE CONTAINING HORSERADISH EXTRACTS
Hyun-Woo Seo1, Ho-Won Park1, Jong-Soo Kim2, Si-Young Lee3, Il-Shik Shin4
1Department of Pediatric Dentistry, College of Dentistry, Gangnuengwonju National University
2Dankook University, Dental College, Dept. of Pediatric Dentistry
3Department of Microbiology and Immunology, College of Dentistry, Gangnuengwonju National University
4Division of Marine Food Science & Technology, College of Life Sciences, Gangnuengwonju National University 
서양산 고추냉이 추출물이 함유된 세치제의 효능에 대한 임상적 실험연구
서현우1, 박호원1, 김종수2, 이시영3, 신일식4
1강릉원주대학교 치과대학 소아치과학교실
2단국대학교 치과대학 소아치과학교실
3강릉원주대학교 치과대학 미생물학및면역학교실
4강릉원주대학교 생명과학대학 해양식품공학과
Correspondence:  Ho-Won Park,  Tel: 033-640-2464, Email: pedo@gwnu.ac.kr
Received: 25 November 2011   • Accepted: 6 February 2012
Abstract
The purpose of this study was to find out the effect of dentifrice containing Horseradish (Armoracia rustica) root extracts on improvement of oral hygiene. The clinical evaluation was done participated by 80 adults volunteers who provided a informed consent for their participation. The participants were divided into two groups ; control group (using toothpaste without Horseradish extracts) and experimental group (using toothpaste containing Horseradish extracts). The checklist of the experiment includes the plaque index, gingival index and anti-caries activity. The anti-caries activity was measured by cultivating Streptococcus mutans for 48 hours then estimating the number of increased bacteria using Dentocult SM. The double-blind method was used in this study. The results of this study can be summarized as follows; 1. The plaque formation decreased 28% in control group, 58% in experimental group using dentifrice with Horseradish extracts compared to baseline data. 2. For gingival index, control group and experimental group showed 26% and 40% decrease compared to baseline data, respectively. 3. The score of caries activity test decreased by 4% for control group and 69% for experimental group compared to baseline data. According to the results, a dentifrice containing Horseradish extracts can improve oral hygiene.
Key Words: Horseradish(Armoracia rusticana) extracts, Ally isothiocyanate(AIT), Dentifrice
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