REMINERALIZATION EFFECTS BY APF GEL AND CPP-ACP PASTE ON INCIPIENT ARTIFICIAL CARIES OF ENAMEL

Kang, Ji-Sun; Lee, Nan-Young; Lee, Sang-Ho

Journal of the Korean Academy of Pediatric Dentistry 2008;35(4):684-691.
Published online November 30, 2008.

REMINERALIZATION EFFECTS BY APF GEL AND CPP-ACP PASTE ON INCIPIENT ARTIFICIAL CARIES OF ENAMEL

Ji-Sun Kang, Nan-Young Lee, Sang-Ho Lee

Department of Pediatric Dentistry, College of Dentistry, Chosun University

법랑질 인공우식병소에서 APF gel과 CPP-ACP 제제의 재광화 효과

강지선, 이난영, 이상호

조선대학교 치과대학 소아치과학교실

Correspondence: Nan-Young Lee, Tel: 062-220-3867, Email: nandent@chosun.ac.kr

Received: 29 May 2008 • Accepted: 16 October 2008

Abstract

Many operations have been carried out using the fluoride ion to prevent and reverse dental caries. It certainly encourages remineralization and also prevents dental caries. However, the remineralization developed by these means is superficial only leaving lower levels of demineralized lesion with a degree of porosity and incomplete mineralization. We must consider its toxic effects when it is ingested for overdose. The CPP-ACP paste is able to remineralize the incipient lesion and has no harmful effects when it is ingested, because it was made form casein which is from the protein of milk. The purpose of this article is to compare the remineralization effects between APF gel and the CPP-ACP paste. we applicated the APF gel and CPP-ACP paste on the artificial enamel carious lesion. After 14 days, we measured the surface microhardness and observed the remineralized lesion under polarized light microscope. The results were as follows : 1. The surface microhardness of group III was the highest, followed by group II, and I(p<0.05). 2. The surface microhardness of group III was significantly higher than those of group I, and II(p<0.05). 3. We could observe thin and irregular remineralization layer of group II, and regular and moderate remineralization layer of group III under polirized light microscope.

Key Words: CPP-ACP, APF gel, Remineralization, Microhardness, Polarized light microscope