Journal of the Korean Academy of Pediatric Dentistry 2008;35(4):607-618.
Published online November 30, 2008.
THE EFFECT OF EMDOGAIN® APPLICATION IN REPLANTED BEAGLE’S ANTERIOR TEETH : 3-DIMENSIONAL AND HISTOLOGIC ANALYSIS
Chan-Yong Eom, Yeung-Chuli Choi, Jae-Hong Park, Sung-Chul Choi
Department of Pediatric Dentistry and Institute of Oral Biology, School of Dentistry, Kyung Hee University 
재식전 건조시간에 따른 Emdogain® 의 적용이 치근흡수에 미치는 영향 : 조직학적, 3차원영상 분석
엄찬용, 최영철, 박재홍, 최성철
경희대학교 치과대학 소아치과학교실
Correspondence:  Sung-Chul Choi,  Tel: 02-958-9371,2, Email: pedochoi@khu.ac.kr
Received: 18 April 2008   • Accepted: 7 August 2008
Abstract
This study three-dimensionally and histologically assessed the effect of Emdogain® on periodontal healing in replanted teeth in three beagle dogs which were 1 to 2 years old, weighing from 10 to 13 ㎏. Twelve maxillary and mandibular incisors were intentionally extracted and replanted after 15(Group I), 30(Group II) and 60(Group III) minutes of air dry storage with and without the application of Emdogain®. The following conclusions could be drawn from the present investigation. 1. Increased incidence of inflammatory healing response in periodontal tissue was proportional to air dry time in Both control and experimental group(P<0.001). 2. Treatment Group showed lower inflammatory root resorption, especially there were statically significant in Group I, III(P<0.001, Group II : P=0.093). 3. Inflammatory root resorption were mainly occurred in apical third(14, 15-16 section)(P<0.05, 0.001), and cervical third(1 section)(P<0.05). 4. In view of horizontal section of long tooth axis, Main root resorption area were 1, 4, 5 line area(bucco-lingual area)(P<0.01).
Key Words: Tooth Avulsion, Replantation, Emdogain®, Dental cone beam CT, Root resorption
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