| PERIODONTOPATHIC BACTERIA IN DOWN'S SYNDROME |
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| 다운증후군 환자의 치주질환 원인균의 출현율 |
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김선미1, 양규호1, 최남기1, 오종석2, 강미선2 |
1전남대학교 치과대학 소아치과학교실 및 치의학연구소
2전남대학교 의과대학 미생물학교실 |
Correspondence:
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| Abstract |
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It is widely known that individuals with Down's syndrome(DS) often develop early onset severe periodontal diseases. In this study, We examined the prevalence of periodontopathic bacteria in DS patients to compare controls with mental disabilities(MD) The subjects were 27 DS patients (7 to 19 years old) and 27 age-matched controls with MD. Plaque index and gingival index were measured. And 5 pathogens, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, were surveyed in subgingival plaque samples using a polymerase chain reaction. No significant difference in plaque index and gingival index were observed between the DS and control group. The prevalence in DS was 96.3% for F. nucleatum, 74.1% for T. forsythia, 63.0% for P. gingivalis, 55.6% for A. actinomycetemcomitans. 40.7% for T. denticola. No significant differences were observed in the prevalence of periodontopathic bacterias between the DS and control. Prevalence of P.g(16.7%) at age 7~10 is lower than other age group in DS, but its prevalence increased with age. Prevalence of A.a(83.3%) is peak at age 7~10 in DS. These results suggest that various periodontopathic pathogens can colo nize in the very early childhood of DS and MD patients. But no significant difference was observed in the prevalence of periodontopathic bacterias between the DS and control. |
| Key Words:
Down/s syndrome, Polymerase chain reaction, Periodontopathic bacteria, Porphyromonas gingivalis, Treponema denticola, Actinobacillus actinomycetemcomitans |
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