TREATMENT OF TOOTH DISCOLORATION ASSOCIATED WITH TRIPLE ANTIBIOTIC THERAPY: CASE REPORTS

Bak, So-Yeon; Kim, Young-Jae; Kim, Jung-Wook; Jan, Ki-Taeg; Lee, Sang-Hoon; Kim, Chong-Chul; Hahn, Se-Hyun; Hyun, Hong-Keun

Journal of the Korean Academy of Pediatric Dentistry 2012;39(1):43-50.
Published online February 29, 2012.

TREATMENT OF TOOTH DISCOLORATION ASSOCIATED WITH TRIPLE ANTIBIOTIC THERAPY: CASE REPORTS

So-Yeon Bak, Young-Jae Kim, Jung-Wook Kim, Ki-Taeg Jan, Sang-Hoon Lee, Chong-Chul Kim, Se-Hyun Hahn, Hong-Keun Hyun

Department of Pediatric Dentistry, School of Dentistry, Seoul National University

미성숙영구치의 복합항생제 적용에 의한 변색의 처치: 증례보고

박소연, 김영재, 김정욱, 장기택, 이상훈, 김종철, 한세현, 현홍근

서울대학교 치의학대학원 소아치과학교실

Correspondence: Hong-Keun Hyun, Tel: 02-2072-0112, Email: hege1@snu.ac.kr

Received: 1 September 2011 • Accepted: 11 January 2012

Abstract

The concept of revascularization of necrotic pulps regained interest and became an alternative conservative treatment option for young permanent teeth with immature roots. Revascularization of immature teeth with apical periodontitis depends mainly on disinfection of the canal. Since the infection of the root canal system is considered to be polymicrobial, a combination of drugs would be needed to treat the diverse flora. A triple antibiotic mixture of metronidazole, ciprofloxacin, and minocycline was used as an intracanal medicament. However, discoloration was developed after applying the triple antibiotic mixture. It is believed that the marked discoloration is related to the use of minocycline. The aim of this article was to present cases of coronal discoloration after triple antibiotic therapy in immature tooth and was treated with bleaching technique to control coronal discoloration. In conclusion, revascularization by using triple antibiotics promotes a paradigm shift in treating endodontically involved permanent teeth. However, we should understand that triple antibiotics containing minocycline induces tooth discoloration. Further research to prevent coronal discoloration should be investigated and suggested for the safe use of triple antibiotics.

Key Words: Triple antibiotics, Metronidazole, Minocycline, Ciprofloxacin, Crown discoloration, Bleaching